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Source Naturals, SAMe, 400 mg, 30 Enteric Coated Tablets

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Original price $45.61
Original price $45.61 - Original price $45.61
Original price $45.61
Current price $27.31
$27.31 - $27.31
Current price $27.31
SKU 021078014003


  • Improved Enteric Coating
  • Dietary Supplement
  • S-Adenosyl-L-Methionine
  • Supports Joint Comfort, Function and Mobility
  • Suitable for Vegetarians

Source Naturals® SAMe is a stable, bioavailable form of S-adenosyl-L-methionine. These tablets are enteric coated and blister packed for consistent quality and optimal bioactivity. SAMe is present in every living cell in the body and plays an important part in many critical cellular functions.

A number of clinical studies have demonstrated that SAMe supplementation supports joint comfort, function and mobility in the spine, hips and knees. Preliminary research suggests that SAMe may work by supporting the production of proteoglycans, which are important components of cartilage.

Numerous clinical studies have also demonstrated that SAMe can help support a positive outlook. It is able to cross the bloodbrain barrier, where it is thought to affect the synthesis of neurotransmitters, and to help maintain normal membrane fluidity. SAMe works together with the B-vitamins, in particular folic acid, making it important to obtain adequate amounts of the B-vitamin complex from diet and supplements.

SAMe plays a key role in transmethylation, a vital type of chemical reaction that affects the synthesis activation, and metabolism of various biological molecules. Compounds that require this reaction include phospholipids, which are fundamental for all cell membrane functions and for cell to cell communication.

Suggested use

1 tablet, 1 to 3 times daily. Take tablets on an empty stomach.

Other ingredients

Cellulose, methacrylic acid copolymer, mannitol, citric acid, stearic acid, silica, hydroxypropyl methylcellulose, triacetin, sodium starch glycolate, modified cellulose gum.

Contains no yeast, dairy, egg, gluten, soy or wheat. Contains no sugar, preservatives, or artificial flavor or fragrance.

Supplement Facts
Serving Size: 1 Tablet
Servings Per Container: 30
Amount Per Servings % Daily Value
SAMe (s-adenosyl-L-methionine) from 800 mg of SAMe disulfate tosylate 400 mg
†Daily Value not established.


If you are pregnant, may become pregnant, breastfeeding or are taking antidepressant medication, consult your physician before using this product. Use this product under medical supervision if you have bipolar disorder. In a small percentage of people this product may cause nausea or gastrointestinal upset. If you experience discomfort, discontinue use.

Do not use if either tamper-evident seal is broken or missing.

Keep out of the reach of children.


While HealthCentralUSA strives to ensure the accuracy of its product images and information, some manufacturing changes to packaging and/or ingredients may be pending update on our site. Although items may occasionally ship with alternate packaging, freshness is always guaranteed. We recommend that you read labels, warnings and directions of all products before use and not rely solely on the information provided by HealthCentralUSA.


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