website Skip to content
Sale Up to 45% OFF! * * Lowest Price Guaranteed
Sale Up to 45% OFF! * * Lowest Price Guaranteed

SAM-e

  • Original price $7.47 - Original price $21.45
    Original price
    $7.47 - $21.45
    $7.47 - $21.45
    Current price $7.47

    NutraLife, SAMe (Disulfate Tosylate), 400 mg, 60 Enteric Coated Caplets

    Description NutraLife™ Health Products Incorporated 400 mg Active S-Adenosyl-Methionine Per Tablet Manufactured in Accordance with GMP Dietary ...

    View full details
    Original price $7.47 - Original price $21.45
    Original price
    $7.47 - $21.45
    $7.47 - $21.45
    Current price $7.47
  • Original price $28.97 - Original price $28.97
    Original price
    $28.97
    $28.97 - $28.97
    Current price $28.97

    Nature's Craft, SAM-e, 90 Capsules

    Description S-Adenosyl Methionine Better Sleep Joint Support Mood Enhancement Cognition & Memory Sleep &...

    View full details
    Original price $28.97 - Original price $28.97
    Original price
    $28.97
    $28.97 - $28.97
    Current price $28.97
  • Original price $23.82 - Original price $23.82
    Original price
    $23.82
    $23.82 - $23.82
    Current price $23.82

    Nature's Craft, SAM-e, 60 Capsules

    Description S-Adenosyl Methionine Better Sleep Mood Enhancement Joint Support Cognition & Memory Sleep & Mood D...

    View full details
    Original price $23.82 - Original price $23.82
    Original price
    $23.82
    $23.82 - $23.82
    Current price $23.82
  • Original price $35.15 - Original price $35.15
    Original price
    $35.15
    $35.15 - $35.15
    Current price $35.15

    Nutricost, SAMe, 200 mg, 120 Capsules

    Description S-Adenosyl-L-Methionine 400 mg Per Serving Dietary Supplement Nutricost® Quality Guarantee Vegetarian Product GMP Compliant Facilit...

    View full details
    Original price $35.15 - Original price $35.15
    Original price
    $35.15
    $35.15 - $35.15
    Current price $35.15
  • Original price $42.02
    Original price $42.02 - Original price $42.02
    Original price $42.02
    Current price $33.62
    $33.62 - $33.62
    Current price $33.62

    Source Naturals, SAMe S-Adenosyl-L-Methionine, 200 mg, 60 Enteric Coated Tablets

    Description Improved Enteric Coating Dietary Supplement Supports Joint Comfort, Function and Mobility Source Naturals® SAMe is a stable, bioav...

    View full details
    Original price $42.02
    Original price $42.02 - Original price $42.02
    Original price $42.02
    Current price $33.62
    $33.62 - $33.62
    Current price $33.62
    Save 20% Save %
  • Original price $7.47 - Original price $21.45
    Original price
    $7.47 - $21.45
    $7.47 - $21.45
    Current price $7.47

    NutraLife, SAMe (Disulfate Tosylate), 400 mg, 30 Enteric Coated Tablets

    Description Double Strength 400 mg Active S-Adenosyl-Methionine Per Tablet Manufactured in Accordance with GMP Dietary Supplement NutraLife SAM...

    View full details
    Original price $7.47 - Original price $21.45
    Original price
    $7.47 - $21.45
    $7.47 - $21.45
    Current price $7.47
  • Original price $7.47 - Original price $21.45
    Original price
    $7.47 - $21.45
    $7.47 - $21.45
    Current price $7.47

    NutraLife, SAMe (Disulfate Tosylate), 200 mg, 60 Enteric Coated Tablets

    Description 200 mg Active S-Adenosyl-Methionine Per Tablet Manufactured in Accordance with GMP Dietary Supplement NutraLife SAMe™ Enteric Coate...

    View full details
    Original price $7.47 - Original price $21.45
    Original price
    $7.47 - $21.45
    $7.47 - $21.45
    Current price $7.47
  • Original price $46.33 - Original price $46.33
    Original price
    $46.33
    $46.33 - $46.33
    Current price $46.33

    Lake Avenue Nutrition, SAMe ( Disulfate Tosylate), 400 mg, 60 Enteric Coated Tablets

    Description Lake Avenue Nutrition SAMe (S-Adenosyl L-Methionine) Featuring SAMe from S-Adenosyl L-Methionine Disulfate Tosylate Suitable for...

    View full details
    Original price $46.33 - Original price $46.33
    Original price
    $46.33
    $46.33 - $46.33
    Current price $46.33
  • Original price $31.31 - Original price $82.66
    Original price $31.31 - Original price $82.66
    Original price $31.31
    $16.28 - $49.50
    $16.28 - $49.50
    Current price $16.28

    Life Extension, SAMe S-Adenosyl-Methionine, 200 mg, 30 Enteric Coated Vegetarian Tablets

    Description Gluten Free Supports Joints and Emotional Well-Being Non GMO LE Certified Dietary Supplement SAMe has multiple mechanisms of actio...

    View full details
    Original price $31.31 - Original price $82.66
    Original price $31.31 - Original price $82.66
    Original price $31.31
    $16.28 - $49.50
    $16.28 - $49.50
    Current price $16.28
    Save up to 40% Save %
  • Original price $31.31 - Original price $82.66
    Original price $31.31 - Original price $82.66
    Original price $31.31
    $16.28 - $49.50
    $16.28 - $49.50
    Current price $16.28

    Life Extension, SAMe S-Adenosyl-Methionine, 400 mg, 60 Enteric Coated Vegetarian Tablets

    Description Gluten Free Supports Joints and Emotional Well-Being Non GMO LE Certified Dietary Supplement SAMe has multiple mechanisms of actio...

    View full details
    Original price $31.31 - Original price $82.66
    Original price $31.31 - Original price $82.66
    Original price $31.31
    $16.28 - $49.50
    $16.28 - $49.50
    Current price $16.28
    Save up to 40% Save %
  • Original price $55.20 - Original price $55.20
    Original price
    $55.20
    $55.20 - $55.20
    Current price $55.20

    Protocol for Life Balance, SAMe, 400 mg, 60 Tablets

    Description Supports Nervous System and Joint Health Stabilized SAMe, Smaller Tablet No Enteric Coating Needed A Dietary Supplement How it Wor...

    View full details
    Original price $55.20 - Original price $55.20
    Original price
    $55.20
    $55.20 - $55.20
    Current price $55.20
  • Original price $27.38 - Original price $27.38
    Original price
    $27.38
    $27.38 - $27.38
    Current price $27.38

    Protocol for Life Balance, SAMe , 200 mg, 60 Veg Capsules

    Description Supports Nervous System and Joint Health Stabilized SAMe, Capsule Form No Enteric Coating Needed Non-GMO A Dietary Supplement Vege...

    View full details
    Original price $27.38 - Original price $27.38
    Original price
    $27.38
    $27.38 - $27.38
    Current price $27.38
  • Original price $25.90 - Original price $25.90
    Original price
    $25.90
    $25.90 - $25.90
    Current price $25.90

    Swanson, SAMe, High Potency, 400 mg, 30 Tablets

    Description Emotional Wellness and Joint Health 400 mg Per Tablet Dietary Supplement Promotes Emotional Wellness, Healthy Mood and Neurotransmi...

    View full details
    Original price $25.90 - Original price $25.90
    Original price
    $25.90
    $25.90 - $25.90
    Current price $25.90
  • Original price $45.61
    Original price $45.61 - Original price $45.61
    Original price $45.61
    Current price $27.31
    $27.31 - $27.31
    Current price $27.31

    Source Naturals, SAMe, 400 mg, 30 Enteric Coated Tablets

    Description Improved Enteric Coating Dietary Supplement S-Adenosyl-L-Methionine Supports Joint Comfort, Function and Mobility Suitable...

    View full details
    Original price $45.61
    Original price $45.61 - Original price $45.61
    Original price $45.61
    Current price $27.31
    $27.31 - $27.31
    Current price $27.31
    Save 40% Save %
  • Original price $78.54
    Original price $78.54 - Original price $78.54
    Original price $78.54
    Current price $47.03
    $47.03 - $47.03
    Current price $47.03

    Now Foods, SAMe, 400 mg, 60 Tablets

    Description Nervous System Support Supports Emotional Well-Being Supports Joint Health Enteric Coated New Oval Tablet Enteric Coated A Di...

    View full details
    Original price $78.54
    Original price $78.54 - Original price $78.54
    Original price $78.54
    Current price $47.03
    $47.03 - $47.03
    Current price $47.03
    Save 40% Save %
  • Original price $31.51
    Original price $31.51 - Original price $31.51
    Original price $31.51
    Current price $18.87
    $18.87 - $18.87
    Current price $18.87

    Natural Factors, SAMe, 200 mg, 30 Enteric Coated Tablets

    Description Dietary Supplement Joint & Mood Support Purity & Potency Guaranteed Non-GMO Documentation, Lab Tested Purity and Pote...

    View full details
    Original price $31.51
    Original price $31.51 - Original price $31.51
    Original price $31.51
    Current price $18.87
    $18.87 - $18.87
    Current price $18.87
    Save 40% Save %
  • Original price $31.31 - Original price $82.66
    Original price $31.31 - Original price $82.66
    Original price $31.31
    $18.75 - $49.50
    $18.75 - $49.50
    Current price $18.75

    Life Extension, SAMe, S-Adenosyl-Methionine, 400 mg, 30 Enteric Coated Tablets

    Description Supports Joints and Emotional Well-Being Non GMO LE Certified Dietary Supplement SAMe has multiple mechanisms of action th...

    View full details
    Original price $31.31 - Original price $82.66
    Original price $31.31 - Original price $82.66
    Original price $31.31
    $18.75 - $49.50
    $18.75 - $49.50
    Current price $18.75
    Save up to 40% Save %
  • Original price $70.14
    Original price $70.14 - Original price $70.14
    Original price $70.14
    Current price $42.00
    $42.00 - $42.00
    Current price $42.00

    California Gold Nutrition, SAMe, Preferred Form Butanedisulfonate, 400 mg, 60 Enteric Coated Tablets

    Description California Gold Nutrition® SAMe, Enteric Coated Supports Healthy Joints, Liver & Mood* Suitable for Vegetarians & Veg...

    View full details
    Original price $70.14
    Original price $70.14 - Original price $70.14
    Original price $70.14
    Current price $42.00
    $42.00 - $42.00
    Current price $42.00
    Save 40% Save %

Real Reviews from Real Customers

Blog posts

Buy the Best SAM-e Supplements Online to Unlock Wellness

SAM-e, or S-adenosylmethionine, is a natural compound that is found in every cell of your body. It involves many biochemical reactions, such as synthesizing neurotransmitters, hormones, and DNA. SAM-e is also a powerful antioxidant and anti-inflammatory agent that can protect your cells from damage and inflammation. 

However, not all SAM-e supplements are the same. There are many factors that you need to consider when choosing the best SAM-e Supplements for your needs and goals. In this article, we will guide you through the process of choosing and using the best SAM-e supplements. We will also review some of the best-selling products on the market and show you how they can help you improve your health and wellness.

Understanding the benefits of SAM-e supplements: A Beacon of Health

SAM-e supplements can provide you with many benefits for your health and wellness, such as:

  • SAM-e for Depression: Elevating Mood Naturally
  • One of the most well-known and researched benefits of SAM-e Supplements is its ability to improve your mood and mental health. SAM-e can help you overcome depression by increasing the levels of serotonin, dopamine, and norepinephrine in your brain. These are neurotransmitters that regulate your mood, cognition, and behavior. SAM-e can also enhance the effects of antidepressant medications, such as selective serotonin reuptake inhibitors (SSRIs), by increasing their availability and potency in your brain.

    SAM-e for depression has been shown to be effective, safe, and well-tolerated in many clinical trials. SAM-e can improve your depressive symptoms, such as low mood, loss of interest, hopelessness, and suicidal thoughts, as well as your quality of life, such as your social and occupational functioning. SAM-e can also improve your cognitive function, such as your memory, attention, and learning, which can be impaired by depression.

  • SAM-e for Anxiety: Calming the Storm Within
  • Another benefit of SAM-e is its ability to calm your anxiety and nervousness. SAM-e can help you reduce your anxiety symptoms, such as excessive worry, nervousness, restlessness, and panic attacks, by increasing the levels of serotonin, dopamine, and norepinephrine in your brain. These are neurotransmitters that regulate your mood, cognition, and behavior. SAM-e can also enhance the effects of anti-anxiety medications, such as benzodiazepines, by increasing their availability and potency in your brain.

    SAM-e for anxiety has been shown to be effective, safe, and well-tolerated in many clinical trials. SAM-e can improve your anxiety symptoms, such as your fear, nervousness, and apprehension, as well as your quality of life, such as your social and occupational functioning. SAM-e can also improve your cognitive function, such as your memory, attention, and learning, which can be impaired by anxiety.

  • SAM-e for Arthritis: Nourishing Joint Health
  • Another benefit of SAM-e Supplements is their ability to nourish your joint health and mobility. SAM-e can help you manage your arthritis symptoms, such as pain, stiffness, and inflammation, by reducing the production of pro-inflammatory cytokines, such as interleukin-1 and tumor necrosis factor-alpha, and increasing the production of anti-inflammatory cytokines, such as interleukin-10 and transforming growth factor-beta. SAM-e can also enhance the effects of anti-inflammatory medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs), by increasing their availability and potency in your joints.

    SAM-e for arthritis has been shown to be effective, safe, and well-tolerated in many clinical trials. SAM-e can improve your arthritis symptoms, such as your pain, stiffness, and swelling, as well as your joint function, such as your range of motion, flexibility, and strength. SAM-e can also improve your quality of life, including physical and emotional well-being.

  • SAM-e Pills: A Convenient Daily Boost
  • One of the most convenient ways to take SAM-e supplements is in pill form. SAM-e pills are easy to swallow and carry, and they can provide you with a consistent and reliable dose of SAM-e. SAM-e pills are also enteric-coated, meaning they have a special layer that prevents them from dissolving in your stomach and allowing them to reach your small intestine.

  • SAM-e Vitamin Supplements: Bridging Essential Gaps
  • Another benefit of SAM-e is that it is a vital "vitamin" for your health and wellness. SAM-e can help you bridge the nutritional gaps arising from your diet, lifestyle, or medications. SAM-e can provide you with the essential nutrients that your body needs to function optimally.

    By providing you with these essential nutrients, SAM-e can help you prevent or correct the deficiencies that may affect your health and well-being.


    Top-Rated SAM-e Supplements: Elevate Your Wellness

    If you are looking for Top-Rated SAM-e Supplements to boost your health and wellness, you have come to the right place. At Health Central USA, we offer a wide range of top-rated SAM-e supplements that can suit your needs and preferences. Here are some of the best-selling products that you can find on our website:

    1. Lake Avenue Nutrition SAM-e Disulfate Tosylate 400 mg: A High-Quality SAM-e Health Supplement for Your Well-Being
    2. If you are looking for a high-quality SAM-e health supplement that can support your mood, liver, joint, and skin health, you may want to consider Lake Avenue Nutrition SAM-e Disulfate Tosylate 400 mg. This product contains 400 mg of SAM-e disulfate tosylate per tablet, which is equivalent to 200 mg of SAM-e. SAM-e, or S-adenosylmethionine, is a natural compound involved in many biochemical reactions in your body, such as synthesizing neurotransmitters, hormones, and DNA. SAM-e can also be a powerful antioxidant and anti-inflammatory agent, protecting your cells from damage and inflammation.

    3. Nutricost SAM-e 200 mg: Unleashing the Power of SAM-e Supplements

      This high-quality SAM-e supplement comes in capsule form. Each capsule contains 200 mg of SAM-e disulfate tosylate, which is equivalent to 100 mg of SAM-e. This product is enteric-coated to ensure its absorption and effectiveness. Third-party labs also test and verify its purity, potency, and stability. Nutricost SAM-e 200 mg can help you improve your mood, liver, joint, and skin health by providing you with a natural and potent source of SAM-e.

    4. California Gold Nutrition SAM-e Preferred Form Butanedisulfonate 400 mg: A Premium SAM-e Health Supplement for Your Health and Happiness
    5. If you are looking for a premium SAM-e health supplement that can support your mood, liver, joint, and skin health, you may want to consider California Gold Nutrition SAM-e Preferred Form Butanedisulfonate 400 mg. This product contains 400 mg of SAM-e butane-disulfonate per tablet, which is equivalent to 200 mg of SAM-. SAM-e, or S-adenosylmethionine, is a natural compound involved in many biochemical reactions in your body, such as synthesizing neurotransmitters, hormones, and DNA. SAM-e can also be a powerful antioxidant and anti-inflammatory agent, protecting your cells from damage and inflammation.

    6. NOW Foods SAM-e 400 mg: Elevate Your Vitality with Every Tablet

      This Top-rated SAM-e supplement comes in tablet form. Each tablet contains 400 mg of SAM-e tosylate disulfate, which is equivalent to 200 mg of SAM-e. This product is enteric-coated to ensure its absorption and effectiveness. Third-party labs also test and verify its purity, potency, and stability. NOW Foods SAM-e 400 mg can help you improve your mood, liver, joint, and skin health by providing you with a natural and potent source of SAM-e.

    7. Life Extension SAM-e S-Adenosyl Methionine 400 mg: A Superior SAM-e S Adenosylmethionine Supplement for Your Well-Being

      If you are looking for a superior SAM-e S Adenosylmethionine Supplement that can support your mood, liver, joint, and skin health, you may want to consider Life Extension SAM-e S-Adenosyl Methionine 400 mg. This product contains 400 mg of SAM-e tosylate disulfate per tablet, which is equivalent to 200 mg of SAM-e. SAM-e, or S-adenosylmethionine, is a natural compound involved in many biochemical reactions in your body, such as synthesizing neurotransmitters, hormones, and DNA. SAM-e can also be a powerful antioxidant and anti-inflammatory agent, protecting your cells from damage and inflammation.

    Start Your Wellness Journey with the Best SAM-e Supplements from Health Central USA


    In the pursuit of optimal well-being, choosing the best SAM-e supplements is a pivotal decision. Trust Health Central USA will guide you through this journey, offering products and a pathway to holistic health.

    Whether you are looking for SAM-e tablets, capsules, or powder, we have the best options for you. Plus, we offer 24-hour chat support, wellness content, and fast delivery to make your shopping experience easy and convenient.

Show More

Compare products

{"one"=>"Select 2 or 3 items to compare", "other"=>"{{ count }} of 3 items selected"}

Select first item to compare

Select second item to compare

Select third item to compare

Compare